Accession Number : ADA336792

Title :   Georgetown Institute for Cognitive and Computational Sciences

Descriptive Note : Annual rept. 30 Sep 96-15 Nov 97

Corporate Author : NATIONAL BIOMEDICAL RESEARCH FOUNDATIONWASHINGTON DC

Personal Author(s) : Ledley, Robert S.

PDF Url : ADA336792

Report Date : DEC 1997

Pagination or Media Count : 151

Abstract : GICCS faculty has begun a major initiative to elucidate the complex mechanisms of higher auditory processing. Species with specialized hearing, such as bats, are used as models for complex sound processing and compared to those using cats and primates, which also use acoustic signals as a primary means of communication. Parallel research in humans using functional brain imaging and cognitive psychology examine how the human brain deals with complex sounds, particularly those relating to speech. These studies address not only normal language processing but also examine disorders of speech/language, including developmental and acquired dyslexias. Understanding and modifying brain plasticity represents another major research area. Investigators use tools from cellular/molecular neurobiology and from systems neuroscience, to study plasticity after acute or chronic brain injury as well as after early vision or hearing loss. This includes development of novel pharmacological strategies to limit brain damage and to enhance cognitive function after injury or neurodegeneration. Brain magnetic resonance techniques (including functional imaging) are also used. Sophisticated computational methods are used to model sensory processing based upon experimental studies. Predictions based upon mathematical modeling are evaluated in subsequent laboratory experiments.

Descriptors :   *AUDITORY ACUITY, *BRAIN DAMAGE, *AUDITORY DEFECTS, *NEUROBIOLOGY, SIGNAL PROCESSING, AGING(PHYSIOLOGY), MAGNETIC RESONANCE, ACOUSTIC SIGNALS, SPEECH RECOGNITION, NERVE CELLS, PERCEPTION(PSYCHOLOGY), PHARMACOLOGY, AUDITORY SIGNALS, AUDITORY PERCEPTION, SPEECH REPRESENTATION.

Subject Categories : Medicine and Medical Research
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE