Accession Number : ADA337490

Title :   Virus Detection: Limits and Strategies.

Descriptive Note : Final rept. Jan 96-Aug 97,

Corporate Author : EDGEWOOD RESEARCH DEVELOPMENT AND ENGINEERING CENTER ABERDEEN PROVING GROUNDMD

Personal Author(s) : Wick, Charles H. ; Yeh, Homer R. ; Carlon, Hugh R. ; Anderson, David

PDF Url : ADA337490

Report Date : DEC 1997

Pagination or Media Count : 23

Abstract : The rapid detection of virus particles is a vexing issue to the military and public health communities. The need for a rapid and trustworthy virus detector remains an urgent and continuing requirement for commanders requiring an assurance that they have early warning from these threats. This short report presents a historical summary, with references, of methods used to extract, purify, and concentrate viruses. Working with viruses is not an easy job. The requirement for detection was identified nearly 60 years ago and just now is seeing an approach with the evolution of the Integrated Virus Detector System (IVDS) device to undertake this exacting and difficult task. This work expounds a new methodology - IVDS. The IVDS utilizes a physical process to detect viruses. This is a departure from the traditional approaches that historically have utilized obscure chemical reactions, complicated reagents and other exacting and difficult procedures for detection. The IVDS is based in four physical stages which are collection, separation, purification, and detection. Development and risks are discussed. An IVDS development schedule and costs are given that could lead to an advance prototype in two years. The IVDS system promises a very sensitive, broad spectrum "generic" virus detector free from reagent based reactions, simple to operate, and providing a capability for continuous monitoring and recording of virus levels in the outdoor bioaerosol.

Descriptors :   *INTEGRATED SYSTEMS, *DETECTORS, *VIRUSES, METHODOLOGY, QUICK REACTION, DETECTION, COMMUNITIES, MONITORING, PHYSICAL PROPERTIES, HEALTH, COSTS, PURIFICATION, PARTICLES, SCHEDULING, CHEMICAL AGENTS, RECORDING SYSTEMS, PUBLIC HEALTH, EARLY WARNING SYSTEMS.

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE