Accession Number : ADA337861

Title :   Statistical Genetics Methods for Localizing Multiple Breast Cancer Genes.

Descriptive Note : Annual rept. 1 Sep 96-31 Aug 97,

Corporate Author : COLUMBIA UNIV NEW YORK

Personal Author(s) : Ott, Jurg

PDF Url : ADA337861

Report Date : SEP 1997

Pagination or Media Count : 26

Abstract : While breast cancer in many families is due to the known breast cancer genes, there is still a sizable proportion of families that do not show linkage to these known genes. Thus, it is important that other genetic loci responsible for these cases be investigated. The past year was mostly spent on developing theory for estimating linkage disequilibrium between a generalized mendelian locus and a nearby marker locus (Task 4). Work is progressing satisfactorily and results will be implemented in a computer program. A manuscript will be written in the next funding period.

Descriptors :   *GENES, *BREAST CANCER, COMPUTER PROGRAMS, THEORY, STATISTICAL PROCESSES, GENETICS, LOCUS.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE