Accession Number : ADA954861

Title :   Development of a Model System for Studies of Malabsorption in Diarrhic Animals.

Descriptive Note : Final rept.,

Corporate Author : INDIANA UNIV AT INDIANAPOLIS SCHOOL OF MEDICINE

Personal Author(s) : Nunn,A. S. , Jr

Report Date : SEP 1971

Pagination or Media Count : 29

Abstract : Galactose per-loaded segments prepared from hamster jejunum have been studied in terms of galactose efflux from the tissue. Evidence is presented for an outward pathway across the apical surface of the mucosal cells which is phloridzin insensitive, not dependent upon tissue sodium concentration or tissue/outside sodium gradients, but highly influenced by apical surface oxygenation. These data indicate an oxygen dependent mechanism other than the absorption pathway for galactose may play role in galactose movement by the mucosal tissue.

Descriptors :   ABSORPTION, ANIMALS, GALACTOSE, GRADIENTS, HAMSTERS, JEJUNUM, MODELS, OXYGEN, SODIUM, SURFACES

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE