Accession Number : ADA955153

Title :   The Mesentric Circulation in Diarrheal Diseases.

Descriptive Note : Final comprehensive rept. 1 Sep 68-30 Jul 73,

Corporate Author : TEXAS UNIV MEDICAL SCHOOL AT HOUSTON

Personal Author(s) : Jacobson,Eugene D.

Report Date : 10 MAY 1972

Pagination or Media Count : 23

Abstract : Investigations were conducted to understand the role of the intestinal circulation in response to naturally occurring vasoactive substances, to drugs, to shock states and to increases in either intestinal motor activity or tension of the gut wall. In addition, the hydrodynamics of a diarrheal model were studied. Primary methods employed included use of anesthetized dogs and monkeys, measurement of mesenteric blood flow, gut and blood preessures with implanted flow or pressure transducers, intraarterial infusion of a variety of vasoactive agents and measurement of tissue enzymes by isotopic methods.

Descriptors :   ARTERIES, BLOOD, BLOOD CIRCULATION, CARDIOVASCULAR AGENTS, CIRCULATION, DIARRHEA, DISEASES, DOGS, DRUGS, FLOW, HYDRODYNAMICS, IMPLANTATION, INFUSIONS, INTESTINES, MODELS, MONKEYS, MOTOR REACTIONS, PERITONEUM, PRESSURE TRANSDUCERS, SHOCK(PATHOLOGY)

Subject Categories : Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE