Accession Number : ADA955168

Title :   Human Platelet Senescence.

Descriptive Note : Annual summary rept. no. 5, 1 Jan 74-31 Dec 74,

Corporate Author : NEW YORK UNIV MEDICAL CENTER N Y

Personal Author(s) : Karpatkin,Simon

Report Date : 31 DEC 1975

Pagination or Media Count : 4

Abstract : Five areas of platelet research related to platelet production and megathrombocyte (young platelet) identification include: Use of an Albumin Density Gradient to identify a Young Platelet Population; Use of the Megathrombocyte to Monitor a Thrombopoietic Stimulus; Splenic Sequestration of Megathrombocytes; Requirement of Iron for Thrombopoiesis, Megathrombopoiesis and Platelet Protein Synthesis; and Identification of a Splenic-Humoral Platelet-Release Factor in Plasma from Animals Subjected to Chronic Blood Loss.

Descriptors :   AGING(PHYSIOLOGY), ALBUMINS, ANIMALS, BIOSYNTHESIS, BLOOD, BLOOD PLATELETS, CHELATION, DENSITY, GRADIENTS, HUMANS, IRON, LOSSES, POPULATION, PRODUCTION, PROTEINS, REQUIREMENTS, SPLEEN

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE