Accession Number : ADA955928

Title :   Detection and Measurement of Antibody-Antigen Reactions.

Descriptive Note : Annual rept.,

Corporate Author : CORDIS CORP MIAMI FL

Personal Author(s) : Murphy, William P., Jr

Report Date : 08 JUN 1962

Pagination or Media Count : 27

Abstract : The current investigation involves an application of a technique developed by Walter B. Dandliker, Ph. D., Professor of Biochemistry, University of Miami School of Medicine. This involves measurements of fluorescence polarization and/or intensity measurements made on solutions which contain fluorescent-labelled antigens or antibodies. This technique was studied in great detail by Doctor Dandliker using fluorescein-labelled ovalbumin and rabbit antifluorescein ovalbumin. Fluorescence polarization measurements were made with a modified light-scattering apparatus. His need for more sophisticated and accurate optical equipment soon became obvious and an improved polarometer was built for by Cordis Corporation. Keywords: U/A Reports, Antibody-antigen reactions, Biochemistry, Chemical analysis, Humoral immunity cellular, Immunity.(jg)

Descriptors :   *ANTIGEN ANTIBODY REACTIONS, *DETECTION, *FLUORESCENCE, *MEASUREMENT, *POLARIZATION, ACCURACY, ANTIBODIES, BIOCHEMISTRY, CHEMICAL ANALYSIS, FLORIDA, HUMORAL IMMUNITY, INTENSITY, LIGHT SCATTERING, MEDICINE, OPTICAL EQUIPMENT, PHYSICIANS, RABBITS, SCHOOLS.

Subject Categories : Biochemistry
      Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE