Accession Number : ADB086227
Title : Design and Synthesis of Candidate Prophylactic and Therapeutic Compounds for Use in the Management of Organophosphorus Poisoning.
Descriptive Note : Annual progress rept. no. 1, 1 Sep 81-31 Aug 82,
Corporate Author : ASH STEVENS INC DETROIT MI
Personal Author(s) : Blumbergs, P. ; Knutson, P. L. ; Priest, M. A. ; Pease, J. P. ; Stevens, C. L.
Report Date : OCT 1982
Pagination or Media Count : 47
Abstract : This program is directed at the design and synthesis of new compounds for use in the management of organophosphorus poisoning. In the past year 14 compounds were submitted for evaluation: nine organophosphinates, one oxophospholane, two aryl N-hydroxy-N-methycarbamates, one piperidine and one dialkylaminoalkyl glycolate ester.
Descriptors : *POISONING, *ORGANIC PHOSPHORUS COMPOUNDS, *CHEMOTHERAPEUTIC AGENTS, PREVENTIVE MEDICINE, SYNTHESIS(CHEMISTRY), PHOSPHINATES, CARBAMATES, PIPERIDINES, ESTERS.
Subject Categories : Toxicology
Distribution Statement : APPROVED FOR PUBLIC RELEASE