Accession Number : ADB102436
Title : Synthesis of New Antimalarial Agents.
Descriptive Note : Interim progress rept. 1 Apr-31 Jul 83,
Corporate Author : RESEARCH TRIANGLE INST RESEARCH TRIANGLE PARK NC
Personal Author(s) : Kepler, John A. ; Carroll, Frank I.
Report Date : AUG 1983
Pagination or Media Count : 35
Abstract : This report pertains to synthesis of New Antimalarial Agents. The objective of this project is to synthesize potential antimalarial compounds of the following types; Peroxides based on qinghaosu; Pro-drugs of primaquine; and Thymidylate synthetase inhibitors. This report describes the work carried out on this contract during the period April 1, 1983 to July 31, 1983.
Descriptors : *ANTIMALARIALS, *PHARMACOLOGY, PEROXIDES, SYNTHASES, SYNTHESIS, PRIMAQUINE, ENZYME INHIBITORS.
Subject Categories : Pharmacology
Distribution Statement : APPROVED FOR PUBLIC RELEASE