Accession Number : ADB105447

Title :   Epidemiological Surveillance of Influenza and Other Respiratory Diseases in Military Personnel.

Descriptive Note : Annual rept. 1 Oct 82-31 May 83,

Corporate Author : COLORADO UNIV HEALTH SCIENCES CENTER DENVER

Personal Author(s) : Meiklejohn, Gordon ; Eickhoff, Theodore C.

Report Date : 31 MAY 1983

Pagination or Media Count : 24

Abstract : The H.I. antibody response of recruits who had received either whole virus vaccine or split vaccine was compared. Response to the whole vaccine was exceptionally good. Response to the ether-split vaccine was, if anything, slightly better. The incidence of febrile URI remained extremely low despite outbreaks of H1N1 and H3N2 influenza A and of influenza B. At no time did the number of cases/1000/week exceed 3.8. It appeared that vaccine had been remarkably effective in providing protection and in reducing transmission. Despite the occurrence of cases of three types over many weeks there was only one week when influenza appeared to have an appreciable effect on overall respiratory disease rates in the student population. Strains of H3N2 influenza A and influenza B were consistently isolated from patients with influenza, but, as in the past, virus isolation was successful in only about 60% of cases of H1N1 influenza. For these serologic diagnosis was essential in order to detect all cases. Other viral diseases occurred only in very small numbers. Three cases of adenovirus diseases were detected. No cases of rubella or rubeola were recognized. Streptococcal cultures were positive in 13% of the patients. Serum from 50 recruits which received the standard military vaccine were tested against the new A/Philippines/2/22 which has been accepted as the A/H3N2 component of the vaccine for the year. Keywords: Hemagglutinin; and Adenovirus.

Descriptors :   *MEDICAL EXAMINATION, *INFLUENZA, *RESPIRATORY DISEASES, ADENOVIRUSES, ANTIBODIES, RESPONSE(BIOLOGY), RATES, RUBELLA, DIAGNOSIS(GENERAL), DISEASES, EPIDEMIOLOGY, SURVEILLANCE, MEASLES VIRUSES, SPLITTING, VACCINES, MILITARY APPLICATIONS, POPULATION, STUDENTS, RECRUITS, MILITARY PERSONNEL, VIRUSES, ISOLATION.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE