Accession Number : ADB105448

Title :   Epidemiological Surveillance of Influenza and Other Respiratory Diseases in Military Personnel.

Descriptive Note : Annual rept. 1 Jun 83-31 Jan 84,

Corporate Author : COLORADO UNIV HEALTH SCIENCES CENTER DENVER

Personal Author(s) : Meiklejohn, Gordon ; Eickhoff, Theodore C.

Report Date : FEB 1984

Pagination or Media Count : 44

Abstract : Despite the presence of H3N2 and H1N1 influenza A and influenza B on the Base during the 1982-83 season, febrile respiratory disease rates remained at unprecedentedly low levels. In order to determine whether the antigenic drift in the new H3N2 strain A/Philippines/2/83 would significantly reduce the effectiveness of A/Bangkok/79 vaccine, sera from Air Force recruits were tested and showed good A/Philippines/82 response to A/Bangkok vaccine. The vaccine response to 1983-84 vaccine of both recruits and permanent party at Lackland Air Force Base was tested in December 1983. While the response of permanent party was slightly lower than that of the recruits, it appeared that the 1983-84 formulations would provide a high degree of protection. When serum pairs from recruits vaccinated in 1982-83 were tested against older H3n2 strains, it was shown that current vaccines would provide a high degree of protection against any of the earlier H3N2 strains. Considerable effort was made to assess the usefulness of various procedures in determining need for antigenic strain composition of the vaccine. The relationship between the oral temperature and the success in isolating virus in influenza patients was compared. Complement fixation tests using RSV antigen of 140 serum pairs collected last spring showed fourfold increases in titer in 3 individuals and twofold increases in titer in an additional 11 persons.

Descriptors :   *RESPIRATORY DISEASES, *INFLUENZA, *MEDICAL EXAMINATION, AIR FORCE FACILITIES, ANTIGENS, DRIFT, EPIDEMIOLOGY, SURVEILLANCE, PROTECTION, INFLUENZA, PATIENTS, MILITARY PERSONNEL, AIR FORCE, RECRUITS, SERODIAGNOSIS, FEVERS, RATES, LOW LEVEL, MOUTH, TEMPERATURE, RECRUITS, BLOOD SERUM, RESPONSE, VACCINES.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE