Accession Number : ADB110949

Title :   Synthesis Laboratory for the U.S. Army Medical Research Institute of Infectious Diseases Selection Panel.

Descriptive Note : Annual progress rept. 1 Dec 85-30 Nov 86,

Corporate Author : SOUTHERN RESEARCH INST BIRMINGHAM AL KETTERING-MEYER LAB

Personal Author(s) : Secrist, John A., III ; Kwong, Cecil D. ; Krauth, Charles A. ; Ford, Angela G.

Report Date : 21 JAN 1987

Pagination or Media Count : 25

Abstract : A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U.S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluations. Types of compounds prepared thus far include 1-benzyloxyadenosines, amidines, 1,2,4,5,3,6-tetraazadiphosphorines, substituted imidazoles, and several compounds derived from ascorbic acid. Keywords: antiviral agents.

Descriptors :   *SYNTHESIS(CHEMISTRY), *CHEMICAL LABORATORIES, *ANTIVIRAL AGENTS, AMIDINES, ARMY RESEARCH, MEDICAL RESEARCH, TEST AND EVALUATION, INFECTIOUS DISEASES, PANELS, SELECTION, SYNTHESIS, VIRUSES, ASCORBIC ACID, PREPARATION, LABORATORIES, IMIDAZOLES, ADENOSINE, AMIDINES.

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE