Accession Number : ADB157007

Title :   Synthesis of Potential Anti-Vesicant Compounds.

Descriptive Note : Annual rept. 18 Dec 89-31 Dec 90,

Corporate Author : ASH STEVENS INC DETROIT MI

Personal Author(s) : Dunkerton, Louis V.

Report Date : 01 MAY 1991

Pagination or Media Count : 30

Abstract : The purpose of this contract is to provide potential antivesicant compounds for the U.S. Army Medical Research and Development Command. In the 12 months, six compounds were submitted from the cysteine derivative class. They include 2(RS)-ethyl thiazolidine-4(R)-carboxylic acid, S-acetyl-N,S-bis-(tert-butoxycarbonyl)-2(R)-aminopropane-1,3-dithiol, N-(tert-butoxycarbonyl)-L-cystine methyl ester, N-(tert-butoxycarbonyl)-L-cystinol, S,S-bis-acetyl-N-tert-butoxy-carbonyl-2-aminopropane-1,3-dithiol, and 3,3'-carbonylbis(ethyl 2-oxothiazolidine-4R-carboxylate).

Descriptors :   , ARMY RESEARCH, CYSTEINE, MEDICAL RESEARCH, SYNTHESIS.

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE