Accession Number : ADB165289
Title : Preparation of Drugs and Bulk Chemical Compounds for the U.S. Army Drug Development Program.
Descriptive Note : Annual rept. 15 Mar 91-14 Mar 92,
Corporate Author : ASH STEVENS INC DETROIT MI
Personal Author(s) : Blumbergs, P. ; Dagil, D. J. ; Tseng, C. C. ; Steriopoulos, P. A. ; Moore, J.
Report Date : 27 MAY 1992
Pagination or Media Count : 65
Abstract : The purpose of this contract is to provide chemical compounds for the U.S. Army Medical R and D Command. In the 12 months, five assignments were completed. Compounds submitted include a phosphinylpentanoic acid, an 8-aminoquinoline intermediate and three potential metabolites of WR 238605. Preparative work on a large, 2.5 kg lot of WR 238605 was completed also and analysis and characterization of the final product is in progress. 8-Aminoquinoline, Antimalarials, Metabolites, Phosphinylpentanoic acid, Synthesis, RA 5.
Descriptors : *ANTIMALARIALS, *SYNTHESIS(CHEMISTRY), *PHARMACOLOGY, CHEMICAL COMPOUNDS, CONTRACTS, METABOLITES.
Subject Categories : Pharmacology
Distribution Statement : APPROVED FOR PUBLIC RELEASE