Accession Number : ADD000106

Title :   Method and Means for Determining Oxyhemoglobin Association and Dissociation Curves of Whole Blood or Other Liquids.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON D C

Personal Author(s) : Runch,Alan H ; Valeri,Cesare Robert

Report Date : 18 Dec 1973

Pagination or Media Count : 13

Abstract : The invention concerns a method and apparatus for the automated measurement of the oxyhemoglobin association and dissociation curves of whole blood, erythrolysates or other liquids. The samples to be measured are studied in an environment of constant hydrogen ion concentration (pH) and temperature. They are initially deoxygenated by continuous flow washing and then are exposed to a linear gradient of increasing oxygen concentration to obtain the oxygenation curve. The samples are then oxygenated by continuous flow washing and next are exposed to a linear gradient of decreasing oxygen concentration to obtain the deoxygenation curve.

Descriptors :   *Patents, *Hemoglobin, *Oxygen, *Measuring instruments, *Bioinstrumentation, Dissociation, Graphs, Temperature, pH factor, Automation, Methodology, Erythrocytes

Subject Categories : Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE