Accession Number : ADD000585

Title :   Radioactive Iodine Labeling of Viruses Enzymes and Flourescene Isothyiocyanate.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON D C

Personal Author(s) : Parikh,Gokaldas C ; Duvall,Charles Steven

Report Date : 07 Jan 1975

Pagination or Media Count : 3

Abstract : The patent describes an in vitro method of labeling viruses, enzymes, and fluorochrome molecules extracellularly in which a phosphate buffered saline solution is combined with a solution of K1 containing I2. Next a predetermined quantity of radioactive iodine-125 is added to the solution. At this point the entity to be labeled is added, and the solution is stirred and allowed to react. A slight excess of sodium thiosulphate is added to convert any unreacted iodine to iodide, and the solution is then dialyzed.

Descriptors :   *Patents, *Labeled substances, *Viruses, *Enzymes, Radioactive isotopes, Iodine, Fluorescence, Molecules

Subject Categories : Biochemistry
      Radiation and Nuclear Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE