Accession Number : ADD000585
Title : Radioactive Iodine Labeling of Viruses Enzymes and Flourescene Isothyiocyanate.
Descriptive Note : Patent,
Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON D C
Personal Author(s) : Parikh,Gokaldas C ; Duvall,Charles Steven
Report Date : 07 Jan 1975
Pagination or Media Count : 3
Abstract : The patent describes an in vitro method of labeling viruses, enzymes, and fluorochrome molecules extracellularly in which a phosphate buffered saline solution is combined with a solution of K1 containing I2. Next a predetermined quantity of radioactive iodine-125 is added to the solution. At this point the entity to be labeled is added, and the solution is stirred and allowed to react. A slight excess of sodium thiosulphate is added to convert any unreacted iodine to iodide, and the solution is then dialyzed.
Descriptors : *Patents, *Labeled substances, *Viruses, *Enzymes, Radioactive isotopes, Iodine, Fluorescence, Molecules
Subject Categories : Biochemistry
Radiation and Nuclear Chemistry
Distribution Statement : APPROVED FOR PUBLIC RELEASE