Accession Number : ADD003874

Title :   Sealing of Glass Ampoules.

Descriptive Note : Patent Application,


Personal Author(s) : Greiff,Donald ; Melton,Hewlett E

Report Date : 22 Dec 1975

Pagination or Media Count : 14

Abstract : A method of sealing gas-filled glass ampules and the like to insure the closure of any microscopic channel existing between the outer and the inner surface thereof, and its product of manufacture is described. After the ampoule is filled and sealed, it and its contents are suitable for storing in ambient or low temperature, or for freezing, or freeze-drying. However, flame-sealing of the ampoules usually results in a small channel through the sealed tip. All typical flame-type sealing methods substantially close the ampoule but the microscopic channel still remains. The presence of the channel is undesirable since it permits gas exchange between the ampoule contents and the outside environment. Therefore, a polymeric coating of neoprene rubber dissolved in toluene or other suitable material is employed to seal the flame-sealed tips of the ampoules to assure closure of any existing channel. (Author)

Descriptors :   *Patent applications, *Ampules, *Hermetic seals, *Rubber coatings, Neoprene, Glass, Gases, Low temperature, Seals(Stoppers)

Subject Categories : Medical Facilities, Equipment and Supplies
      Adhesives, Seals and Binders

Distribution Statement : APPROVED FOR PUBLIC RELEASE