Accession Number : ADD005492

Title :   Detection and Estimation of Microquantities of Alkylating Agents.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE ARMY WASHINGTON D C

Personal Author(s) : Epstein,Joseph ; Heggie,Robert M ; Norman,John J

Report Date : 11 Apr 1978

Pagination or Media Count : 4

Abstract : This patent covers a method comprising an unknown solution adding an organophosphorus thio acid salt solution for sufficient time to form compounds having anticholinesterase activity in the reaction solution, contacting the reaction solution with a cholinesterase supported on a suitable substrate, adding indoxyl acetate and observing a noncolor or blue color change in the substrate; the absence of color indicates the formation of compounds with anticholinesterase activity and the blue color of the substrate indicating that there was no formation of compounds with anticholinesterase activity.

Descriptors :   *Patents, *Mustard agents, *Chemical agent detectors, Nitrogen mustards, Sulfur compounds, Protection, Chemical reactions

Subject Categories : Chemical, Biological and Radiological Warfare

Distribution Statement : APPROVED FOR PUBLIC RELEASE