Accession Number : ADD006857

Title :   Novel Prostaglandin Derivatives, Certain in vivo and in vitro Effects Thereof and Processes for the Preparation of Same.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC

Personal Author(s) : Polis,B David ; Polis,Edith

Report Date : 08 May 1979

Pagination or Media Count : 14

Abstract : The novel prostaglandis PGBx are useful for a wide variety of in vivo and in vitro biological properties, including the reversal of degenerative changes in mitochondria, the protection of the heart against cardiac insults, the protection and reversal of anoxic damage to the brain, and the improvement of mammalian performance for conditioned psychological tasks. These prostaglandins PGB sub x are prepared, for example, by the base catalyzed reaction of PGB sub 1. (Author)

Descriptors :   *Patents, *Prostaglandin, Chemical derivatives, Mitochondria, Heart, Protection, Performance(Human), Conditioned response

Subject Categories : Biochemistry
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE