Accession Number : ADD007642

Title :   Ammonia-Cyanoborane, Sodium Iodide Complex.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE ARMY WASHINGTON DC

Personal Author(s) : Spielvogel,Bernard F ; McPhail,Andrew T ; Hall,Iris H ; Wisian-Neilson,Patty ; Hargrave,Karl D

Report Date : 24 Jun 1980

Pagination or Media Count : 5

Abstract : Preparation of the crystalline complex (Na(NH3.BH2(CN))6)I from NMe3.BH2I and NaCN in liquid NH3 is disclosed. Structural details of this novel octahedral complex are obtained by single-crystal X-ray analysis. Evidence indicates that the complex is a valuable antiarthritic agent, since it completely inhibits bacteria-induced chronic arthritis in rats with no evidence of toxic effects. The complex also possesses analgesic and anti-inflammatory activity. (Author)

Descriptors :   *Patents, *Chemotherapeutic agents, *Boranes, *Sodium compounds, *Iodides, *Complex compounds, Ammonia, Crystals, Preparation, Synthesis(Chemistry), Arthritis, Analgesics, Ammonium compounds, Molecular structure, Crystal structure

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE