Accession Number : ADD009118

Title :   Liposome Carriers in Leishmaniasis Chemotherapy with 8-Aminoquinoline Derivatives.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE ARMY WASHINGTON DC

Personal Author(s) : Steck,Edgar A ; Alving,Carl R

Report Date : 24 Nov 1981

Pagination or Media Count : 5

Abstract : An improved method is provided for the chemotherapy of leishmanial infections. An 8-aminoquinoline antileishmanial agent is encapsulated within liposomes and the liposome-encapsulated drug is injected into the body. Subject use of a liposome carrier has produced marked enhancement of the effectiveness of the drug against leishmanial parasites in the liver (such as characteristic of infections which are difficult to treat). (Author)

Descriptors :   *Patents, *Leishmaniasis, *Chemotherapy, Encapsulation, Efficiency

Subject Categories : Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE