Accession Number : ADD010374

Title :   2-Acetyl and 2-Propionylpyridine Thiosemicarbazones as Antimalarials.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE ARMY WASHINGTON DC

Personal Author(s) : Klayman,Daniel L ; Scovill,John P ; Bartosevich,Joseph F ; Mason,Carl J ; Griffin,T Scott

Report Date : 24 May 1983

Pagination or Media Count : 8

Abstract : This invention relates to various 2-acetyl- and 2-propionylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infection. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.

Descriptors :   *Patents, *Antimalarials, Amines, Thiourea, Synthesis(Chemistry), Methyl radicals, Ethyl radicals, Alkyl radicals, Heterocyclic compounds, Gonorrhea, Malaria, Infectious diseases

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE