Accession Number : ADD010590

Title :   Method for Treating Gonorrhea Infections with 2-Acetyl- and 2-Propionylpyridine Thiosemicarbazones.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC

Personal Author(s) : Klayman,Daniel L ; Scovill,John P ; Bartosevich,Joseph F ; Mason,Carl J ; Griffin,T Scott

Report Date : 30 Aug 1983

Pagination or Media Count : 25

Abstract : This invention relates to various 2-acetyl- and 2-propionylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infection. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones. (Author)

Descriptors :   *Patents, *Antimicrobial agents, *Antimalarials, *Gonorrhea, Chemotherapy, Malaria, Bacterial diseases, Synthesis(Chemistry), Salts, Alkyl radicals, Methyl radicals, Ethyl radicals, Carboxylic acids, Esters, Nitrogen, Cyclic compounds, Ammino compounds

Subject Categories : Medicine and Medical Research
      Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE