Accession Number : ADD011860

Title :   Anti-Trypanosomal Activity of Platinum Co-Ordination Compounds.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE ARMY WASHINGTON DC

Personal Author(s) : Wysor,M S ; Zwelling,L A

Report Date : 30 Jul 1985

Pagination or Media Count : 4

Abstract : A novel method has been developed for improved chemotherapy of animals infected with African trypanosomiais. The method involves the concurrent administration of therapeutically effective amounts of cis-diamminedichloroplatinum (II) and bis-(diethylthiocarbamoyl)disulfide (disulfiram) or diethyl dithiocarbamate to the hydrated animal. (Author)

Descriptors :   *PATENTS, *ANTIPARASITIC DRUGS, *PLATINUM COMPOUNDS, *CARBAMATES, CHEMOTHERAPY, TRYPANOSOMIASIS, ORGANOMETALLIC COMPOUNDS

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE