Accession Number : ADD012741
Title : Esters of Boron Analogues of Amino Acids.
Descriptive Note : Patent,
Corporate Author : DEPARTMENT OF THE ARMY WASHINGTON DC
Personal Author(s) : Spielvogel,Bernard F ; McPhail,Andrew T ; Hall,Iris H
Report Date : 03 Mar 1987
Pagination or Media Count : 4
Abstract : Ester analogues of boron analogues of amino acid are disclosed. Also disclosed is a method of forming the ester analogues in high yield by condensation of the corresponding acids and alcohols with dicylohexylcarbodiimide at room temperature in dichloromethane. The disclosed compounds have shown interesting biological activities, in particular, hypolipidemic activity as well as significant antitumor and antiarthritic activities.
Descriptors : *PATENTS, *BORON, *SYNTHESIS(CHEMISTRY), *CHEMOTHERAPEUTIC AGENTS, *AMINO ACIDS, *ESTERS, ACIDS, ALCOHOLS, BIOLOGY, CHLOROMETHANES, CONDENSATION, HIGH RATE, ROOM TEMPERATURE, IMIDES, LIPIDS, ARTHRITIS, CHOLESTEROL, GLYCERIDES
Subject Categories : Biochemistry
Distribution Statement : APPROVED FOR PUBLIC RELEASE