Accession Number : ADD012747

Title :   Transition Metal Complexes of the Selenium Analogs of 2-Acetyl- and 2-Propionylpyridine Thiosemicarbazones Useful for Treating Malarial Infections and Leukemia.

Descriptive Note : Patent,

Corporate Author : DEPARTMENT OF THE ARMY WASHINGTON DC

Personal Author(s) : Scovill,John P ; Klayman,Daniel L ; Franchino,Charles F

Report Date : 14 Apr 1987

Pagination or Media Count : 15

Abstract : This invention relates to novel transition metal complexes of 2-acetyl-and 2-propionylpyridine thiosemicarbazones, their selenium analogs. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones and their selenium analogs.

Descriptors :   *PATENTS, *METAL COMPLEXES, *PYRIDINES, LEUKEMIA, ANALOGS, SELENIUM, INFECTIOUS DISEASES, MALARIA, TRANSITION METALS

Subject Categories : Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE