Accession Number : ADD013325
Title : Conversion of Prostaglandin Analogs into a Bicarbonate Insoluble Oligomeric Mixture.
Descriptive Note : Patent, Filed 6 May 83, patented 5 May 87,
Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC
Personal Author(s) : Nelson, George L
Report Date : 05 May 1987
Pagination or Media Count : 4
Abstract : A method for oligomerization of a group of prostaglandin analogs such as the Ethyl Analog 3-(trans-3-keto-1-pentenyl1)-2ethyl-2-cyclopentenone into a biologically active exhibiting protection of oxidative phosphorylation of degenerated mitochondria and sodium bicarbonate insoluble oligomeric mixtures is described. The Ethyl Analog is treated with ethanolic potassium hydroxide solution in an oxygen-free atmosphere at moderate conditions of temperature, time and concentration.
Descriptors : *PATENTS, *POLYMERIZATION, BICARBONATES, CONVERSION, ETHANOLS, ETHYL RADICALS, HYDROXIDES, MIXTURES, OXIDATION, PHOSPHORYLATION, POTASSIUM, PROSTAGLANDIN, SODIUM COMPOUNDS, SOLUTIONS(MIXTURES), CHEMICAL ANALOGS, CHEMICAL DERIVATIVES
Subject Categories : Polymer Chemistry
Distribution Statement : APPROVED FOR PUBLIC RELEASE