Accession Number : ADD013646

Title :   Flow-Through Cell Cultivation System.

Descriptive Note : Patent Application, Filed 1 Jun 87,

Corporate Author : DEPARTMENT OF THE AIR FORCE WASHINGTON DC

Personal Author(s) : Kiel, Johnathan L

Report Date : 01 Jun 1987

Pagination or Media Count : 31

Abstract : The present invention relates generally to cell incubators, and more specifically to a novel flow-through chamber for exposing cells immobilized on microcarrier beads to precisely controlled temperatures and to radiation. In vitro (outside a living organism) culturing of cells in cell incubators provides material needed for research in pharmacology, physiology, toxicology and radiation effects. Cell incubators also provide an environment for testing the response of living cells to exposure of drugs, especially new anti-cancer drugs, to exposure of toxicological materials and to exposure of radiation, without requiring experiments on more sentient living things. Cell incubators may also be used to produce valuable cellular products such as monoclonal antibodies and recombinant DNA products.

Descriptors :   *CELLS(BIOLOGY), *PATENT APPLICATIONS, *INCUBATION, *CULTURES(BIOLOGY), ANTIBODIES, CLONES, DEOXYRIBONUCLEIC ACIDS, DRUGS, EXPOSURE(GENERAL), GENETIC ENGINEERING, IN VITRO ANALYSIS, LIFE(BIOLOGY), PHYSIOLOGY, RADIATION, TOXICOLOGY, LABORATORY EQUIPMENT, GROWTH(PHYSIOLOGY), INDUCED ENVIRONMENTS, MICROWAVES, TEMPERATURE CONTROL

Subject Categories : Biology

Distribution Statement : APPROVED FOR PUBLIC RELEASE