Accession Number : ADD015197

Title :   Replacements for Hydrogen Peroxide for Use With Horseradish Peroxidase in Immunoassay.

Descriptive Note : Patent Application, Filed 30 Sep 91,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC

Personal Author(s) : Kidwell, David

Report Date : 30 Sep 1991

Pagination or Media Count : 16

Abstract : This invention pertains to improving stability of immunoassays by using a more stable component. More specifically, this invention pertains to the use of a stable source of hydrogen peroxide in a peroxidase enzyme assay wherein the source releases hydrogen peroxide on contact with water. In an enzyme assay, presence or quantity of a biological substance is determined in a sample of a biological fluid. Although there is a continuous need in medical practice, in research, and and in diagnostic procedures for rapid and accurate determination of biological fluids at low concentration, problems have remained where hydrogen peroxide has been used to activate a peroxidase enzyme.

Descriptors :   ACCURACY, ASSAYING, BIOLOGY, CONDIMENTS, DETERMINATION, DIAGNOSIS(GENERAL), ENZYMES, FLUIDS, HYDROGEN PEROXIDE, IMMUNOASSAY, MEDICINE, PEROXIDASES, RELEASE, SOURCES, STABILITY, WATER

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE