Accession Number : ADD015789

Title :   Polymerizable Lipids in the Development of Controlled Release Carriers.

Descriptive Note : Patent Application, Filed 23 Feb 93,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC

Personal Author(s) : Singh, Alok ; Schnur, Joel M

Report Date : 23 Feb 1993

Pagination or Media Count : 24

Abstract : The present invention provides novel polymerizable lipids and mixtures thereof with non-polymerizable lipids and methods for the controlled release of encapsulated materials using stabilized or polymerized vesicles. Release is induced by pH, ions, temperature, light or other changes in the environment. Time release mechanisms are also employed. Applications of the present invention especially include encapsulation of enzymes and their subsequent sustained release for degradation of environmental pollutants, encapsulation of fluorescent markers for use in sensor systems, and encapsulation and release of fregrant molecules in detergents.

Descriptors :   *LIPIDS, *POLYMERS, *LIPOSOMES, *PATENT APPLICATIONS, *POLYMERIZATION, CAVITIES, BIODETERIORATION, ENCAPSULATION, HYDROPHOBIC PROPERTIES, PHOSPHOLIPIDS, SURFACE ACTIVE SUBSTANCES, ENZYMES

Subject Categories : Organic Chemistry
      Biochemistry
      Polymer Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE