Accession Number : ADD016557

Title :   Light Emission-Or-Absorbance-Based Binding Assays for Polynucleic Acids.

Descriptive Note : Patent, Filed 15 Jan 93, patented 26 Jul 94,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC

Personal Author(s) : Kidwell, David A

Report Date : 26 Jul 1994

Pagination or Media Count : 25

Abstract : A target polynucleic acid strand may be detected within a sample. A sensing strand of complementary polynucleic acid is labelled, at at least two internucleotide phosphate groups, with labels which vary their electronically interaction with each other, and thus their emission or absorption spectra, depending upon whether the sensing strand is bound to target polynucleic acid in the sample.

Descriptors :   *ABSORPTION SPECTRA, *EMISSION, *PATENTS, *LIGHT, *NUCLEOTIDES, *NUCLEIC ACIDS, INTERACTIONS, LABELS, PHOSPHATES, STRANDS, TARGETS, ELECTRONICS, ENZYMES, ANTIBODIES, IMMUNOASSAY, DETECTION

Subject Categories : Biochemistry
      Organic Chemistry
      Optics
      Atomic and Molecular Physics and Spectroscopy

Distribution Statement : APPROVED FOR PUBLIC RELEASE