Accession Number : ADD017689

Title :   Freeze Dried Red Blood Cells and Platelets.

Descriptive Note : Patent Application, Filed 30 Jun 95,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC

Personal Author(s) : Spargo, Barry J

PDF Url : ADD017689

Report Date : 30 Jun 1995

Pagination or Media Count : 16

Abstract : Blood is a major tissue of the human body, and has a predominant role in the delivery of oxygen from the lungs to peripheral tissues. This role is carried out by erythrocytes, i.e., red blood cells (RBC). The oxygen is furnished to the peripheral cells from the lungs by an exchange-diffusion system brought about by a red, iron-containing protein called hemoglobin. When hemoglobin combines with oxygen, oxyhemoglobin is formed and after oxygen is given up to the tissues, the oxyhemoglobin is reduced to deoxyhemoglobin. The red cell membrane is composed of two major structural units, the membrane bilayer and a cytoskeleton. A lipid bilayer and integral membrane proteins form the membrane bilayer. The other major component, the membrane skeleton, stabilizes the membrane bilayer and provides shape and structural integrity. The cytoskeleton is linked to the bilayer in the erythrocyte membrane by lipid-protein as well as protein-protein associations. The hemoglobin, and other RBC components such as glycolytic enzymes, are contained within the red cell membrane.

Descriptors :   *PATENT APPLICATIONS, *FREEZE DRYING, *CELLS(BIOLOGY), *BLOOD PLATELETS, *BLOOD CELLS, FIBERS, DELIVERY, MEMBRANES(BIOLOGY), TISSUES(BIOLOGY), STRUCTURAL PROPERTIES, ENZYMES, PROTEINS, IRON, OXYGEN, RELIABILITY, LUNG, HUMAN BODY, HEMOGLOBIN, ERYTHROCYTES, CELL STRUCTURE, SKELETON, GLYCOSIDASES

Subject Categories : Medicine and Medical Research
      Biology

Distribution Statement : APPROVED FOR PUBLIC RELEASE