Accession Number : ADD017951

Title :   Liposomes Containing Polymerized Lipids for Non-Covalent Immobilization of Proteins and Enzymes.

Descriptive Note : Patent, Filed 30 Mar 94, patented 14 Nov 95,

Corporate Author : DEPARTMENT OF THE NAVY WASHINGTON DC

Personal Author(s) : Singh, Alok

Report Date : 14 Nov 1995

Pagination or Media Count : 19

Abstract : Thc lipids of this invention are derivatives of phosphatidyl choline having the general chemical formula: wherein at least one of R and R' is a polymerizable unsaturated alkyl group, acid or ester, wherein X includes an iminodiacetic acid in the polymerizable metal chelating lipid (2) and wherein z is an integer from 1-20 including 1 and 20. Lipid microstructures are formed by mixing the polymerizable metal chelating lipid monomers (2) with polymerizable non-chelating lipid monomers wherein X includes a non-chelating group, for example, N1(CH3)3.

Descriptors :   *ENZYMES, *LIPIDS, *LIPOSOMES, *POLYMERIZATION, *PROTEINS, *PATENTS, METALS, CHEMICALS, CHELATION, COVALENT BONDS, FORMULATIONS, MONOMERS

Subject Categories : Polymer Chemistry
      Inorganic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE