Accession Number : ADP001984

Title :   JP-10 Metabolism in Male Fischer Rats,

Corporate Author : AIR FORCE AEROSPACE MEDICAL RESEARCH LAB WRIGHT-PATTERSON AFB OH

Personal Author(s) : Inman,Roger C. ; Yu,K. O. ; Serve,M. P.

Report Date : AUG 1983

Pagination or Media Count : 14

Abstract : This paper describes ongoing research to characterize the biological fate of JP-10 in rats. JP-10 is the fuel used in the Air Force's Air-Launched Missile and in other types of cruise missiles. The purpose of this research was to identify the major metabolites of JP-10 in a mammalian system and to determine the routes and kinetics of excretion of the fuel. A simple technique for identification of a major JP-10 metabolite in urine would be a valuable occupational medicine tool to monitor workers for overexposure to JP-10 during production, testing, and handling of cruise missiles. Also, the distribution and fate of the fuel in specific tissues should provide insight to relate exposure to signs and symptoms observed and to indicate which organs have a higher potential for injury.

Descriptors :   *Toxicology, *Metabolism, *Jet engine fuels, *Rocket fuels, *Symposia, Toxicity, Metabolites, Rats, Routing, Kinetics, Excretion, Identification, Urine, Anatomical models, Industrial medicine, Monitoring, Industrial personnel, Exposure(Physiology), Dosage, Signs and symptoms, Neoplasms

Distribution Statement : APPROVED FOR PUBLIC RELEASE