Accession Number : ADP003866

Title :   Role of Reticuloendothelial and Endothelial Cells in Response to Trauma and Shock,

Corporate Author : STATE UNIV OF NEW YORK DOWNSTATE MEDICAL CENTER BROOKLYN

Personal Author(s) : Altura,B. M.

Report Date : 29 APR 1983

Pagination or Media Count : 31

Abstract : Although there is at present no agreement among shock experts as to the etiological or sustaining mechanisms of low-flow state syndromes, evidence has accumulated to suggest that circulatory shock induced by such diverse factors as trauma, hypovolemia, cardiac tamponade, and septicemia, among others, often results in renal failure, liver failure, and a condition known as shock lung. The compromise of such diverse organ systems has led to the concept that shock is a condition of multiple organ failure. Since the intimal surfaces of the vascular system in the form of endothelial cells (EC) and reticuloendothelial system (RES) cells are vital to preserve (and protect) the integrity of organs and tissues, it must be entertained that these cell types could be pivotal in the etiology and progression of shock syndromes, as has been suggested recently. This paper will focus on the importance and interaction of EC and RES cell function with microcirculatory integrity and function in shock and trauma.

Descriptors :   *Trauma, *Shock(Pathology), Reticuloendothelial system, Endothelium, Stimulation(Physiology), Blood circulation, Histamine, Antihistaminics, Symposia

Distribution Statement : APPROVED FOR PUBLIC RELEASE