Accession Number : ADP003872

Title :   Immunotherapy of Trauma,

Corporate Author : CINCINNATI UNIV OHIO DEPT OF SURGERY

Personal Author(s) : Loose,L. D. ; Girard,A. E. ; Larson,D. L. ; Stinnett,J. D.

Report Date : 29 APR 1983

Pagination or Media Count : 12

Abstract : The attractiveness of immunomodulator therapy for infectious disease in burns is that it abrogates the potential development of antibiotic-resistant strains of bacteria, and in addition, the spectrum of activity of an immuno-therapeutant may be considerably greater than that observed using the classical antibiotic therapy. The present studies have focused on a clinically relevant model of immunosuppression, thermal injury, in examining the therapeutic efficacy of synthetic immunomodulators. The model of immuno-suppression was used to optimize the anti-infective activity of the immuno-therapeutants.

Descriptors :   *Trauma, *Immunology, *Therapy, *Drugs, Burns(Injuries), Infectious diseases, Models, Anatomical models, Guinea pigs, Symposia

Distribution Statement : APPROVED FOR PUBLIC RELEASE