Accession Number : ADP004022

Title :   Organophosphorus-Induced Delayed Neurotoxicity: Syndrome and Experimental Models,

Corporate Author : STAUFFER CHEMICAL CO FARMINGTON CT TOXICOLOGY DEPT

Personal Author(s) : Sprague,G. L. ; Bickford,A. A. ; Castles,T. R.

Report Date : AUG 1984

Pagination or Media Count : 7

Abstract : This study was conducted to compare neurotoxicity in hens and rats produced by tri-o-cresyl phosphate (TOCP) delayed neurotoxicant. A metabolic inhibitor, piperonyl butoxide, was co-administered with TOCP in rats in an attempt to reduce their resistance to organophosphate-induced delayed neurotoxicity.

Descriptors :   *Toxicology, *Organic phosphorus compounds, *Esters, Neurology, Metabolism, Inhibition, Rats, Chickens, Dosage, Body weight, Symposia

Distribution Statement : APPROVED FOR PUBLIC RELEASE