Accession Number : ADP004033

Title :   The Toxicity of Complex Mixtures,


Personal Author(s) : MacFarland,H. N.

Report Date : AUG 1984

Pagination or Media Count : 7

Abstract : In discussing the topic of the toxicity of complex mixtures, a definition of what we mean by complex is required. I shall consider any mixture of toxicants containing two or more components as complex. Statisticians have proposed various mathematical models to describe a number of types of toxicological action that mixtures may exhibit and I shall touch on these briefly. In addition, It will outline some studies on two component air pollutant mixtures and also another study with a mixture containing several hundred components to show how toxicologists, in fact, deal with these problems and to what extent they refer to these mathematical models in current practice.

Descriptors :   *Toxicology, *Gasoline, Toxicity, Mixtures, Lead compounds, Blood analysis, Rats, Exhaust gases, Males, Females, Comparison, Symposia

Distribution Statement : APPROVED FOR PUBLIC RELEASE