Accession Number : ADP006555

Title :   Space Flight and Immune System,

Corporate Author : TURIN UNIV (ITALY)

Personal Author(s) : Cogoli, A.

Report Date : APR 1992

Pagination or Media Count : 10

Abstract : Depression of lymphocyte response to mitogens in cosmonauts after spaceflight was reported for the first time in the early seventies by Soviet immunologists. Today we know that depression of lymphocyte function affects at least 50% of space crew members. Investigations on the ground on subjects undergoing physical and psychological stress indicate that stress is a major factor in immune depression of astronauts. This despite the fact that weightlessness perse has a strong inhibitory effect of lymphocyte activation in-vitro. Although the changes observed never harmed the health of astronauts, immunological changes must be seriously investigated and understood in view of long-duration flights on space stations in an Earth orbit and to other planets like Mars and the Moon.

Descriptors :   *ASTRONAUTS, *IMMUNOLOGISTS, *LYMPHOCYTES, *SPACE STATIONS, *WEIGHTLESSNESS, *AEROSPACE MEDICINE, CREWS, EARTH ORBITS, FLIGHT, FUNCTIONS, HEALTH, MOON, ORBITS, PLANETS, RESPONSE, SPACE CREWS, STATIONS, USSR, STRESS(PSYCHOLOGY).

Subject Categories : Medicine and Medical Research
      Manned Spacecraft

Distribution Statement : APPROVED FOR PUBLIC RELEASE