Accession Number : ADP006580

Title :   Future Approaches to Vaccine Development Single-Dose Vaccines Using Controlled-Release Delivery Systems,

Corporate Author : WORLD HEALTH ORGANIZATION GENEVA (SWITZERLAND)

Personal Author(s) : Aguado, Dr. M. T.

Report Date : APR 1992

Pagination or Media Count : 2

Abstract : The development of new vaccines, both more efficacious and easier to deliver, has become an area of research that can certainly benefit from recent technical developments. In particular, the conversion of multiple-dose vaccines into single-dose vaccines may represent an important advance which should lead to improved vaccination coverage, as well as to a reduction in vaccination costs. In order to be fully immunized against diphtheria, pertussis, tetanus, poliomyeltis and hepatitis B, the successive administration of three doses is needed. In many developing countries the drop-out rates from individuals receiving the first dose, but not successive doses is high and can reach values of up to 70 %.

Descriptors :   *HEPATITIS, *IMMUNIZATION, BENEFITS, CONVERSION, COSTS, DROPS, MANAGEMENT, RATES, REDUCTION, TETANUS, VACCINES, VALUE.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE