Accession Number : ADP006589

Title :   Correlation of Serum Alpha sub 1 Antitrypsin with Cigarette Smoking and Pulmonary Function Status in Greek Pilots, for a Ten Year Period,

Corporate Author : HELLENIC AIR FORCE TECHNICAL RESEARCH CENTER ATHENS (GREECE)

Personal Author(s) : Palermos, J. ; Kyriakos, K. ; Michalopoulou, S. ; Daskalopoulos, Ch. ; Bitsaktsis, A.

Report Date : APR 1992

Pagination or Media Count : 3

Abstract : Quantitative and mainly qualitative aberration of the Alpha 1 Antitrypsin (a1AT) a major constituent of the human antielastase screen, it strictly associated with the development of lung emphysema. Certain factors like cigarette smoking and environmental pollution may contribute to that. In this study we have correlated cigarette smoking with the serum a1AT concentration as well with the trend of the predicted values of Forced Vital Capacity (FVC) and lst Second Forced Expiratory Volume (FEV1) over a ten years period. The study population consisted of 113 randomly selected male pilots, of the Greek Air force, being in flight duties grouped into non smokers (n = 49, age x = 36-3) and effective smokers (n=64, age x=38.4) smoking for more than ten years.

Descriptors :   *EMPHYSEMA, FLIGHT, HUMANS, LUNG, MALES, PILOTS, POPULATION, VALUE.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE