Accession Number : ADP007181

Title :   Bandit Strategies for Ethical Sequential Allocation,

Corporate Author : MICHIGAN UNIV ANN ARBOR DEPT OF STATISTICS

Personal Author(s) : Hardwick, Janis P. ; Stout, Quentin F.

Report Date : 1992

Pagination or Media Count : 4

Abstract : The problem of allocating patients in a two treatment clinical trial with dichotomous response is considered. The trial goal is to determine the better treatment while incurring as few patient losses as possible. Several allocation rules are compared and it is found that bandit strategies perform well on both criteria in that they achieve nearly optimal power while keeping expected trial failures nearly minimal. The rules are also evaluated according to their computational complexity.

Descriptors :   *HEALTH, ALLOCATIONS, FAILURE, LOSSES, PATIENTS, POWER, RESPONSE, STRATEGY.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE