Accession Number : ADP008345

Title :   Identification of the Binding Pharmacophores of Vasoactive Intestinal Peptide (VIP),

Corporate Author : HOFFMANN-LA ROCHE INC NUTLEY NJ

Personal Author(s) : Bolin, David R. ; Cottrell, Jeanine M. ; Senda, Ryuko ; Merritt, Douglas ; Garippa, Ralph

Report Date : 1992

Pagination or Media Count : 2

Abstract : Vasoactive Intestinal Peptide (VIP) is an octacosapeptide found in mammalian airway tissue and is proposed to be an endogenous mediator of tracheobronchial smooth muscle relaxation. VIP was the subject of several previous SAR studies.

Descriptors :   *PEPTIDES, BRONCHITIS, MUSCLE RELAXANTS, ANALOGS, POTENCY, RECEPTOR SITES(PHYSIOLOGY).

Subject Categories : Biochemistry
      Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE