Accession Number : ADP008345
Title : Identification of the Binding Pharmacophores of Vasoactive Intestinal Peptide (VIP),
Corporate Author : HOFFMANN-LA ROCHE INC NUTLEY NJ
Personal Author(s) : Bolin, David R. ; Cottrell, Jeanine M. ; Senda, Ryuko ; Merritt, Douglas ; Garippa, Ralph
Report Date : 1992
Pagination or Media Count : 2
Abstract : Vasoactive Intestinal Peptide (VIP) is an octacosapeptide found in mammalian airway tissue and is proposed to be an endogenous mediator of tracheobronchial smooth muscle relaxation. VIP was the subject of several previous SAR studies.
Descriptors : *PEPTIDES, BRONCHITIS, MUSCLE RELAXANTS, ANALOGS, POTENCY, RECEPTOR SITES(PHYSIOLOGY).
Subject Categories : Biochemistry
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE