Accession Number : ADP008360
Title : Conformational Studies of the Amyloid Protein of Alzheimer's Disease,
Corporate Author : MASSACHUSETTS INST OF TECH CAMBRIDGE
Personal Author(s) : Halverson, Kurt J. ; Anderson, Todd ; Spencer, Richard G. ; Auger, Michele ; McDermott, Ann E.
Report Date : 1992
Pagination or Media Count : 3
Abstract : The presence of extracellular amyloid plaque is characteristic of the Alzheimer's disease (AD) brain. The amyloid consists of a 42 amino acid protein known as the beta protein, in reference to the fact that the plaque contains regular cross-beta fibrillar structure as observed by X-ray fiber diffraction.
Descriptors : *PROTEINS, BRAIN, AMINO ACIDS, X RAYS, CRYSTALLOGRAPHY, NUCLEAR MAGNETIC RESONANCE, PEPTIDES, IN VIVO ANALYSIS.
Subject Categories : Biochemistry
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE