Accession Number : ADP008371

Title :   Calcium Binding of Acyclic Peptides: NMR and Computational Studies,

Corporate Author : MCMASTER UNIV HAMILTON (ONTARIO)

Personal Author(s) : Saint Jean, A. ; Cheesman, B. ; Ananthanarayanan, V. S.

Report Date : 1992

Pagination or Media Count : 2

Abstract : Much insight has been obtained on Ca(2+)-binding proteins from studies on cyclic peptides as well as on relatively large linear peptides with sequences resembling the ion-binding regions of these proteins. With the aim of delineating the minimal conformational features required for Ca(2+) binding, we synthesized several short linear peptides and examined their interaction with Ca+ by CD, NMR and molecular modeling methods.

Descriptors :   *CALCIUM, *CATIONS, *PEPTIDES, PROTEINS, NUCLEAR MAGNETIC RESONANCE, CHEMICAL BONDS, CANADA.

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE