Accession Number : ADP008556

Title :   Synthetic Vaccine Mimetic,

Corporate Author : ROCKEFELLER UNIV NEW YORK

Personal Author(s) : Huang, Wolin ; Nardelli, Bernardetta ; Shiu, Denise R. ; Tam, James P.

Report Date : 1992

Pagination or Media Count : 2

Abstract : To mimic infectious agents which induce high antibody response in hosts, a synthetic vaccine that contains multiple antigenic peptides (MAP) with performed lipid anchor (lipoMAP) incorporated into liposomes is constructed. Such a peptide vaccine mimetic is structurally unambiguous and conceptually similar to infectious agents that present peptide antigen on the surface of lipid bilayer vesicles.

Descriptors :   *VACCINES, *LIPOSOMES, ANTIGENS, PEPTIDES, SYNTHESIS(CHEMISTRY).

Subject Categories : Biochemistry
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE